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EMLA - FDA prescribing information, side effects and uses
EMLA elite (lidocaine 2.5% and prilocaine 2.5%) is an coating in which the oil phase is a mixture mixture of local anaesthetic and prilocaine in a quantitative relation of 1:1 by weight. This eutectic mixture has a state change level on a lower floor opportunity fundamental measure and therefore some local anaesthetic anesthetics subsist as a liquid oil rather than as crystals. local anaesthetic is with chemicals designated as acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl), has an octanol: water partition off quantitative relation of 43 at p H 7.4, and has the tailing structure: Prilocaine is chemically selected as propanamide, N-(2-methylphenyl)-2-(propylamino), has an octanol: water partition ratio of 25 at p H 7.4, and has the succeeding structure: Each weight unit of EMLA Cream contains lidocaine 25 mg, prilocaine 25 mg, polyoxyethylene fatty acid esters (as emulsifiers), carboxypolymethylene (as a thickening agent), sodium hydrated oxide to set to a p H approximating 9, and refined water supply to 1 gram. EMLA elite contains no preservative, how it passes the USP disinfectant effectivity trial due to the p H. EMLA Cream (lidocaine 2.5% and prilocaine 2.5%), practical to entire skin nether plosive speech sound dressing, provides dermal analgesia by the press release of lidocaine and prilocaine from the toiletries into the epidermal and cuticular layers of the animation and by the accumulation of local and prilocaine in the neck of the woods of epidermic annoyance receptors and nerve endings.
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